Conclusion: The findings of improved hydration and elasticity were also confirmed in the subgroup meta-analysis. Based on results, ingestion of hydrolyzed collagen for 90 days is effective in reducing skin aging, as it reduces wrinkles and improves skin elasticity and hydration.
PubMed 33742704 ↗Hydrolyzed Collagen
People mainly take Hydrolyzed Collagen for recovery, skin & hair. Based on 8 first-hand reports and 6 meta-analyses & systematic reviews in the medical literature. Ranked #443 of 1,974 overall.
Of reports that state an outcome, 81% are positive.
What Hydrolyzed Collagen does, according to users
Of the people who reported each effect, the share who said it got better.
3 more with fewer than 3 reports
What the research says
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.
Conclusion: The study also identified several biases in the included RCTs. Overall, the findings suggest that HC supplementation can have positive effects on skin health, but further large-scale randomized control trials are necessary to confirm these findings.
PubMed 37432180 ↗Conclusion: In this systematic review, three different mechanisms of action were clarified for the intervention. Direct effects of collagen peptides on fibroblasts, M2-like macrophages, and oral tolerance-related mechanisms are the possible mechanisms for the beneficial effects of collagen supplementation.
PubMed 32436266 ↗Conclusion: Hydrolyzed collagens or collagen peptides with molecular sizes ranging from <3 to 3000 KDa promote the stimulation of fibroblasts in human tissues.
PubMed 38892477 ↗Dosage people report
As stated by users — not a recommendation. Follow the label or your doctor.
Reported side effects
How often each side effect came up across all reports.
What users say
Verbatim quotes, shortened only — each links to the original discussion.
“Oral supplementation for at least 8 weeks improves skin hydration and elasticity”
“Hydrolyzed Collagen (Great Lakes), Hyaluronic Acid (Injuv, DoNotAge)”
“taking 5–15 grams of hydrolyzed collagen combined with 50–250 mg of vitamin C about 30 to 60 minutes before exercise effectively doubles collagen synthesis”
“Hydrolyzed collagen for back pain (result from auto accident and also fall from horse) that had lasted for decades.”
“Hyrolyzed Collagen – Great Lakes – For improved joint and skin health”
Top discussions (5)
- I owe my mom a massive apology because I’ve been calling her daily collagen powder a scam for years ↗
- Looking more youthful? ↗
- New 2023 hydrolyzed collagen meta-analysis concluded improved skin hydration and elasticity ↗
- 37 year old male with worn out knees... Should I start a Glucosamine regimen? ↗
- Dr Rhonda Patrick’s Supplements List ↗
Other options for recovery
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate