Guayusa
People mainly take Guayusa for energy. Based on 8 first-hand reports and 0 meta-analyses & systematic reviews in the medical literature. Ranked #573 of 1,974 overall.
Of reports that state an outcome, 100% are positive.
What Guayusa does, according to users
Of the people who reported each effect, the share who said it got better.
What the research says
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
1–4 randomized controlled trials, no meta-analysis yet. The grade measures how much human research exists — read the conclusions below for what it found.
Dosage people report
As stated by users — not a recommendation. Follow the label or your doctor.
Reported side effects
How often each side effect came up across all reports.
What users say
Verbatim quotes, shortened only — each links to the original discussion.
“Yerba mate and guayusa (regularly) instead of coffee.”
“Lucidity: Huperzine A, Schizandrol A, Guayusa, Guarana, Caffeine, Galantamine, Wormwood, Sage.”
“Use guayusa, don't drink coffee.”
“Guayusa even better.”
“Guayusa. It’s mostly caffeine, but feels much better than coffee or mate.”
Top discussions (5)
- Caffine + L-theanine is absolutely magical for me. What could I do to try and bring my baseline nearer to it? ↗
- After about 1 year with maté. Conclusion: Yerba mate is the best source of caffiene and I am clueless to why we prefer coffee over it. ↗
- Caffeine makes me feel great, Coffee makes me feel terrible? ↗
- Which are the best anti-fatigue and/or pro-energy compounds that you know of? Ok, stimulants and modafinil, but apart from that? Is there anything else which reliably increases energy (in the positive sense) or decreases fatigue (in the negative sense)? ↗
- Any stack tips for "Chill Energy"? (let me explain). ↗
Other options for energy
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate