Conclusion: The results of this systematic review suggest that several herbal medicines, via their multifactorial physiological influences, present as potential options to enhance the treatment of migraine. However, further high-quality research is essential to examine their efficacy and safety as a treatment for migraine.
PubMed 32310327 ↗Feverfew
The short answer. There isn't much data on Feverfew yet — 18 mentions, 3 with a clear outcome — so treat these numbers as anecdotal. It is most often used for pain & inflammation: 100% of 8 reports say that improved. There is a moderate body of research — 9 meta-analyses and 8 trials.
From 18 mentions in total — the rest didn't say how it went and aren't counted.
What Feverfew does, according to users
Of the people who reported each effect, the share who said it got better.
What the research says
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
At least one meta-analysis, or 5+ randomized controlled trials. The grade measures how much human research exists — read the conclusions below for what it found.
Conclusion: German Commission E, a regulatory body that evaluates the safety and efficacy of herbs on the basis of clinical trials, cases, and other scientific literature, has established indications and dosage recommendations for many herbal therapies. Pharmacists have a responsibility to educate themselves about herbal therapies in order to help patients discern the facts from the fiction, avoid harm, and gain what benefits may be available.
PubMed 10030529 ↗Conclusion: The modality of data collection and reporting in the individual studies does not support a pooling of results, but does suggest benefit of feverfew in migraine prophylaxis for at least subsets of the population with the disorder. Pharmacologically, there is some potential for concern with long-term dosing given its cyclooxygenase-2 inhibiting effects and longer-term studies will be needed to ameliorate these concerns in coronary disease patients.
PubMed 22435410 ↗Conclusion: The efficacy of feverfew for the prevention of migraine has not been established beyond reasonable doubt.
PubMed 10908545 ↗Dosage people report
As stated by users — not a recommendation. Follow the label or your doctor.
Reported side effects
How often each side effect came up across all reports.
What users say
First-hand experiences, quoted verbatim. We show one positive and one negative where both exist.
“I rely on the herb Feverfew to make them vanish like a magic trick. No side effects.”
“Feverfew from Now Foods helps me a lot. It's one of the only scientifically supported herbs for head pain...doesn't work for a lot of migraine sufferers.”
“magnesium glycinate and feverfew extract works better than prescribed medications for me.”
“Butterbur and Feverfew can supposedly help with migraines though I have no experience with them.”
Top discussions (5)
- Women who biohacked severe period pain: what actually worked? (Please help!!) ↗
- Studies seem to suggest Feverfew herb (and not pure parthenolide) could have a somewhat unique and paradoxical ability to regenerate axons in the Central Nervous system. ↗
- What can be taken for preventing migraines related to serotonin surge/drop vasodilation? ↗
- Suggestions for Chronic Migraine ↗
- Advice seeking, what botanicals would you take if were me? Vessel issues. Already on omega 3s, vit d3k2, mag glycinate. ↗
Other options for pain & inflammation
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 3, 2026. How we rate