B6
People mainly take B6 for mood, focus, energy. Based on 36 first-hand reports. Ranked #163 of 1,974 overall.
45
User score
Mixed22% positive3% mixed19% negative56% unclear
Of reports that state an outcome, 50% are positive.
Clinical research
Research pending
What B6 does, according to users
Of the people who reported each effect, the share who said it got better.
3 more with fewer than 3 reports
betterno changeworse
What the research says
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
Research data for B6 is being compiled.
Dosage people report
As stated by users — not a recommendation. Follow the label or your doctor.
dailyas reported
full DVdaily
50 mgas reported
low dosesas reported
morningas reported
5-10 mgdaily
Reported side effects
How often each side effect came up across all reports.
neuropathy ×1numbness ×1neurological issues ×1intolerance ×1peripheral neuropathy ×1anxiety ×1nerve damage ×1inflammation ×1
What users say
Verbatim quotes, shortened only — each links to the original discussion.
“Methyl B12, Folate, and B6”
“I've experimented with Magnesium/Zinc/B6 and that's been ok”
“I use b6 ( active form), hydroxy b12, magnesium glycinate, and folinic acid (the folate type I can handle) and creatine.”
“B6”
“Yes I take B6 and B12, lots of evidence that they fight the effects of stress on the brain”
Top discussions (5)
- What’s the #1 supplement that changed everything for you? ↗
- My life got terribly ruined by an SSRI antidepressant I took for only about 25 days in July of 2019. Please give me something to help this I’m so desperate ↗
- What supplements do you think are must-haves for everyone? ↗
- Incredibly simple ADHD "stack". If you have "cyclical" ADHD symptoms, this could be the reason why. ↗
- B12 was the missing link for what I've been looking for ever since I got into Noots ↗
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User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate