Ayahuasca
People mainly take Ayahuasca for mood. Based on 4 first-hand reports. Ranked #763 of 1,974 overall.
21
User score
Mixed50% positive25% mixed25% negative0% unclear
Of reports that state an outcome, 50% are positive.
Clinical research
Research pending
What Ayahuasca does, according to users
Of the people who reported each effect, the share who said it got better.
betterno changeworse
What the research says
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
Research data for Ayahuasca is being compiled.
Dosage people report
As stated by users — not a recommendation. Follow the label or your doctor.
No doses stated in the reports so far.
Reported side effects
How often each side effect came up across all reports.
No side effects reported so far.
What users say
Verbatim quotes, shortened only — each links to the original discussion.
“For the first time, I’ve tried psychedelics - Ayahuasca. ... know how much of a life-changing experience it is.”
“after 2 full retreats, it’s definitely not my medicine.”
“Ayahuasca, DMT, psilocybin (magic mushrooms) and LSD are hands down some of the best substances for this”
“Giving me a relief of 1-2 days and rarely 3-4 days Ketamine, LSD, MDMA, Psilocybin, 5-MEO-DMT, Ayahuasca”
Top discussions (4)
- Long post alert: Give me a life rx to overhaul my life/start over ↗
- 🤙👌How I Managed to Increase my Income 5x, Travel Asia and South and North America & Start Working With Hollywood Celebrities Using BioHacking👇 ↗
- How Can We Enhance Empathy with Nootropics and Other Means of Cognitive Enhancement? ↗
- Which nootropics relieve depression in maximum 3 days (and if possible in a few hours)? ↗
Other options for mood
Resistance Training
Lifestyle · 53 reports
100% report better mood
Mostly positive
Retatrutide
Peptide · 298 reports
69% report better mood
Mostly positiveBResearch: Moderate
Caffeine + L-Theanine
Supplement · 46 reports
100% report better mood
Mostly positive
Tirzepatide
Medication · 219 reports
76% report better mood
Mostly positiveAResearch: Strong
Creatine Monohydrate
Supplement · 139 reports
88% report better mood
Mostly positiveAResearch: Strong
Magnesium Malate
Supplement · 103 reports
100% report better mood
Mostly positiveDResearch: None
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate