1p-LSD
People mainly take 1p-LSD for anxiety, mood, energy. Based on 6 first-hand reports and 0 meta-analyses & systematic reviews in the medical literature. Ranked #966 of 1,974 overall.
Of reports that state an outcome, 50% are positive.
What 1p-LSD does, according to users
Of the people who reported each effect, the share who said it got better.
What the research says
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
No randomized controlled trials in humans found on PubMed. The grade measures how much human research exists — read the conclusions below for what it found.
Dosage people report
As stated by users — not a recommendation. Follow the label or your doctor.
Reported side effects
How often each side effect came up across all reports.
What users say
Verbatim quotes, shortened only — each links to the original discussion.
“1P-LSD seems to be almost similar to the real deal though. I'm currently trying to buy it in powder form and I'll make a PG solution out of it.”
“Using drugs and chemicals in doses that haven't really been tested in long term human trials is another matter. It's an unknown risk.”
“I've been microdosing 1P-LSD with a bit of success. Can replace caffeine pretty easily, it's just a matter of getting the dose right and waiting long enough for it to kick in.”
Other options for anxiety
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate