PlainPill

Elderberry

People mainly take Elderberry for immunity. Based on 16 first-hand reports and 6 meta-analyses & systematic reviews in the medical literature. Ranked #725 of 1,974 overall.

22
User score
Mostly positive
19% positive6% mixed0% negative75% unclear

Of reports that state an outcome, 76% are positive.

Clinical research
AStrong research base
6
meta-analyses
15
RCTs
546
papers

What Elderberry does, according to users

Of the people who reported each effect, the share who said it got better.

betterno changeworse

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

AStrong research base

3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.

Complement Ther Med · 2019 · Meta-analysis / systematic review
Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: A meta-analysis of randomized, controlled clinical trials

Conclusion: The quantitative synthesis of the effects yielded a large mean effect size. These findings present an alternative to antibiotic misuse for upper respiratory symptoms due to viral infections, and a potentially safer alternative to prescription drugs for routine cases of the common cold and influenza.

PubMed 30670267 ↗
Nutrients · 2022 · Meta-analysis / systematic review
Select Dietary Supplement Ingredients for Preserving and Protecting the Immune System in Healthy Individuals: A Systematic Review

Conclusion: Whereas some studies may point to evidence for benefit, specific gaps preclude the authors from making firm statements with regard to the overall evidence-base for these products and ingredients and in answering the research questions. As we move toward a vision of health promotion and resilience rather than a sole focus on disease prevention and treatment, further work in this area of dietary supplements is of utmost importance.

PubMed 36364865 ↗

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

dailyas reported
one medicine cap fullmorning and night
at first symptomsas reported
after workas reported

Reported side effects

How often each side effect came up across all reports.

No side effects reported so far.

What users say

Verbatim quotes, shortened only — each links to the original discussion.

“2 Capsules Elderberry Extract from Nutra Champs”
Source discussion ↗
“Look up elderberries. They seem to do incredible things to the immune system”
Source discussion ↗
“I have had a very high rate of success taking a full medicine cap full of elderberry liquid (I use NOW brand) every morning and night for a few days.”
Source discussion ↗
“I'm taking daily NAC, D3, and elderberry, and if I or anyone I know appears to be heading towards cytokine storm I'd start using (or recommending) high dose NAC and stop the elderberry.”
Source discussion ↗
“elderberry”
Source discussion ↗
Top discussions (5)

Other options for immunity

User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate