Side-by-side comparison
Pick two or three substances to compare user results, effects, side effects and research.
| Tirzepatide Medication | Retatrutide Peptide | |
|---|---|---|
| User score | 70 | 73 |
| Verdict | Mostly positive | Mostly positive |
| Reports | 219 | 298 |
| Research | AResearch: Strong | BResearch: Moderate |
| Meta-analyses / RCTs | 214 / 132 | 22 / 6 |
| Mainly used for | Weight lossAppetiteMood | Weight lossEnergyAppetite |
| Weight loss % reporting improvement | 94% (98) | 92% (146) |
| Appetite % reporting improvement | 85% (33) | 69% (42) |
| Focus % reporting improvement | 100% (2) | 100% (4) |
| Energy % reporting improvement | 56% (16) | 74% (57) |
| Sleep % reporting improvement | 83% (6) | 33% (15) |
| Anxiety % reporting improvement | — | 67% (3) |
| Mood % reporting improvement | 76% (17) | 69% (26) |
| Performance % reporting improvement | 88% (8) | 92% (26) |
| Recovery % reporting improvement | — | 100% (7) |
| Pain & inflammation % reporting improvement | 100% (4) | 75% (8) |
| Digestion % reporting improvement | 33% (3) | 43% (7) |
| Libido % reporting improvement | 50% (4) | 22% (9) |
| Hormones % reporting improvement | — | 100% (12) |
| Blood sugar % reporting improvement | 60% (5) | — |
| Heart & lipids % reporting improvement | 83% (6) | 75% (8) |
| Common side effects | nausea, anhedonia, constipation, fatigue | nausea, stomach issues, fatigue, increased heart |
| Typical dose reported | 7.5 mg | 1-5 mg per week / weekly |