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Caffeine, nicotine, alcohol and other everyday psychoactive substances. 144 rated.
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A–Z
Goal
Any
Weight loss
Appetite
Focus
Energy
Sleep
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Mood
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Research
Any
Moderate or strong
Strong only
3 results
1
56
Ephedrine
Substance
Energy
Focus
Performance
50%
report better
Appetite
2 reports
Mixed
A
Research: Strong
2
42
Black Coffee
Substance
Focus
Appetite
Energy
100%
report better
Appetite
2 reports
Mostly positive
B
Research: Moderate
3
28
Tesofensine
Substance
Mood
Energy
Weight loss
100%
report better
Appetite
3 reports
Mostly positive
B
Research: Moderate
Best substances — ranked by user results & research — PlainPill